The special ride begins at 2nd & Main downtown and runs for nearly 70 miles through communities south of the capital city and back again.
About 250 bicyclists (both cycling racers and casual riders) will take off at 8 a.m. and head south all the way to Wrightsville and Sardis before making their way back to downtown.
Five local restaurants with some of the city's best known chefs will be setup at the finish line for the Pop on Main festival at the conclusion of the ride.
Riders are expected to roll through the finish line between 11 a.m. and 1 p.m.
Armstrong is expected to arrive in Little Rock late tonight. Some of his cycling friends are also taking part in the ride.